Mounjaro. Low to start, once a week.
A weekly tirzepatide pen that acts on two appetite hormones, GLP-1 and GIP. It’s approved in Japan for type 2 diabetes, so for weight loss it’s off-label use. A doctor decides whether it suits you.
Mounjaro first-order set
Tirzepatide 2.5mg · 4 weekly pensYour first month: four weekly pens at 2.5mg, a low starting dose so your body can adjust.
Low to start, then step by step
Illustration only, at the fastest pace. Your doctor sets each step.
- For new patients, once only. After your first month, unless you change or cancel it in My Page, Mounjaro Trial Step 2 starts (3 months, 12 pens, ¥147,000).
- Approved in Japan for type 2 diabetes. Prescribing it for weight loss is off-label use. Japan’s Relief System for Sufferers from Adverse Drug Reactions doesn’t cover off-label use.
- Consults are free. You pay for medicine only if a doctor prescribes it. Prices include tax.
- Private care (jiyū shinryō): not covered by public health insurance.
- Doctors licensed in Japan
- Free consults and follow-ups
- Pay for medicine only if prescribed
It works with your appetite.
Tirzepatide acts like two gut hormones, GLP-1 and GIP, that help regulate appetite. In clinical trials, weight loss was reported when it was paired with diet and exercise. Results vary.
- 1Your stomachFuller for longerFood leaves your stomach more slowly, so you stay full for longer.
- 2Your appetiteQuieter hungerIt acts on the brain’s appetite centre, turning down the “I’m hungry” signal.
- 3Your blood sugarSteadier after mealsIt helps keep your blood sugar steadier after you eat.
Weekly, daily, or a tablet.
Your doctor recommends what fits, and you can change it later.
WeeklyWegovySemaglutide · weekly penA weekly GLP-1 pen, approved in Japan for obesity disease.From ¥24,800 a month
DailyRybelsusSemaglutide · daily tabletA GLP-1 tablet, if you’d rather not inject.From ¥187 a day
DailyVictozaLiraglutide · daily penA GLP-1 pen you use once a day.From ¥44,060 a month
Prescription only: a free consult with a doctor licensed in Japan comes first, and the doctor may decide not to prescribe. Private care (jiyū shinryō): not covered by public health insurance. Prices include tax. For illustration only. Mounjaro, Rybelsus and Victoza: Approved in Japan for type 2 diabetes. Prescribing it for weight loss is off-label use. Japan’s Relief System for Sufferers from Adverse Drug Reactions doesn’t cover off-label use. Wegovy is approved in Japan for obesity disease.
Eligible? Then step by step.
All online, no clinic visits. Screens are for illustration.
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01About 5 minutes
Check you’re eligible
A few questions about your health, your weight and any medicine you take, the pill included. Only your doctor sees them.
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02Free · video consult
Talk to a doctor
A doctor licensed in Japan checks treatment suits you and shows you how to use the pen. We’ll ask for photo ID.
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03Free follow-ups · video or chat
Step by step
Your doctor checks in and decides whether, and when, to raise your dose.
Most care ends at the consult. That’s where we start.
Your weekly dose, logged in a few taps.
A reminder on dose day and a quick log after each pen, which your doctor can see too. The screen is for illustration.
- Pick a spot, inject, log it
- Free follow-ups, by video or chat
- Your doctor decides each dose step with you
Three weeks in a row. How’s your stomach been? Let’s talk about your next step before week 5.
What off-label means.
Mounjaro is approved in Japan for type 2 diabetes, not for weight loss. Before anything is prescribed, your doctor explains what off-label use means for you, including the risks.
- A doctor decides whether it suits you
- Free consults, first and follow-up
- Ask anything before you start
Before you start.
Who can take it?
Adults 18 and over with a BMI of 27.5 or more, or 23 or more with a weight-related health risk, such as high blood pressure, type 2 diabetes or dyslipidaemia. A doctor decides: even with a high BMI, treatment may not be suitable.
Who shouldn’t take it?
It isn’t for anyone pregnant, breastfeeding or planning a pregnancy, anyone with type 1 diabetes or a history of pancreatitis, or anyone with a personal or family history of medullary thyroid cancer or MEN2. Tell your doctor about any allergies and every medicine you take.
Is it approved for weight loss in Japan?
No. Approved in Japan for type 2 diabetes. Prescribing it for weight loss is off-label use. Japan’s Relief System for Sufferers from Adverse Drug Reactions doesn’t cover off-label use. A medicine with the same active ingredient, Zepbound, is approved in Japan for obesity disease.
Can I take it if I’m on the pill?
Mounjaro can affect how well tablets are absorbed, so the pill may work less well. For 4 weeks after you start, and after each dose step-up, a back-up method such as condoms is recommended. Always tell your doctor you take the pill.
How do I inject it?
Once a week, on the same day, at any time. Inject under the skin of your stomach, thigh or upper arm, and change the spot each week. Each pen is one dose, and a step-by-step guide comes with it.
What happens after the first month?
The first-order set is 4 pens of 2.5mg, about a month, delivered once. After it, unless you change or cancel it in My Page, Mounjaro Trial Step 2 starts (3 months, 12 pens, ¥147,000). Your doctor decides whether, and when, to raise your dose.
What are the side effects?
The most common are nausea, diarrhoea and constipation, especially when you start or step up a dose, and they often settle. Get help straight away for severe stomach pain that doesn’t go away, which may be pancreatitis, or for signs of low blood sugar if you take diabetes medicine.
When am I charged?
Consults are free, first and follow-up. You pay for medicine only once a doctor prescribes it. If medicine isn’t right for you, you pay nothing.
Start low. Step up with your doctor.
A few questions to see if you’re eligible, then a free video consult.
- Free consults
- Off-label for weight loss in Japan